To effectively prevent biofilms, which are prevalent in chlorinated drinking water
distribution systems, the effect of biofilm age on antimicrobial resistance must be
investigated. In this study, young and mature biofilms of Pseudomonas aeruginosa, a
model biofilm organism, were grown and exposed to antimicrobial agents in several
different treatments. Results showed that the increased antimicrobial resistance in biofilm
cells compared to planktonic cells arises early in biofilm development. The short-term
tolerance of resuspended mature biofilm cells to antimicrobial agents peaked at a biofilm
age of 14 days, and subsequently declined, whereas the antimicrobial resistance of
resuspended mature biofilm cells continuously exposed to antimicrobial agents increased
with biofilm age. Furthermore, individual members in mature biofilm communities
exhibited variation in antimicrobial resistance. Includes 3 references.
| Edition : | Vol. - No. |
| File Size : | 1
file
, 230 KB |
| Note : | This product is unavailable in Ukraine, Russia, Belarus |
| Number of Pages : | 4 |
| Published : | 06/01/2006 |
