This document specifies a high-performance liquid chromatographic (HPLC) mass spectrometric (MS)
method for screening and quantification of melamine and cyanuric acid in the concentration range
between 1 mg/kg and 100 mg/kg feed.
The method is validated in an international collaborative trial for melamine in complete feed,
complementary feed, feed material, milk replacer and pet food including canned pet food in the range
between 1 mg/kg and 80 mg/kg with particular regard to the maximum level of 2,5 mg/kg as established
by the European Commission.
Laboratory experiences have shown that the method is also applicable for cyanuric acid in the same
concentration range in complete feed (
n = 7), complementary feed (
n = 6), feed material (
n = 7, resp. 9), milk replacer (
n = 7) and pet food (
n = 7) including canned pet food.
Since the LC-MS/MS sensitivity for cyanuric acid is lower than for melamine, it has to be ensured that the
LC-MS/MS system is in excellent working order. The method is applicable to feeding stuffs but not tested
for pre-mixtures and feed additives.
Quantification of concentrations above 100 mg/kg is possible, but the method has to be validated by the
operator.
Cross References:ISO 3534-2:2006
EN ISO 6498:2012
EN ISO/IEC 17043:2010
ISO/IEC Guide 99:2007
ISO 24276:2006
ISO 16577:2016
EN ISO 6497
ISO 5725-2:1994
ISO 11843-2
ISO 5725-1
All current amendments available at time of purchase are included with the purchase of this document. | File Size : | 1
file
, 1.6 MB |
| ISBN(s) : | 9780580932236 |
| Note : | This product is unavailable in Ukraine, Russia, Belarus |
| Number of Pages : | 40 |
| Product Code(s) : | 30337118, 30337118, 30337118 |
| Published : | 09/12/2019 |
