Breast Cancer: Prognosis, Treatment, and Prevention PDF

Preface

Since the first edition of Breast Cancer: Prognosis, Treatment and Prevention was published there has been a tremendous amount of new information related to the basic and clinical applications of this disease which can affect 1 of 8 people in the USA and 1 of 12 in European countries.

This second edition of the book: Breast Cancer: Prognosis, Treatment and Prevention contains recent and very new information on the process of breast carcinogenesis, new prognostic factors and methods of prevention, the role of the breast as an intracrine organ, the enzymatic control in the bioformation and transformation of different hormones in the breast tissue, and the recent advances in the hormonal and non-hormonal treatment of breast cancer.

This second edition was made possible through spontaneous and strong support from the contributors to the first edition, as well as the enthusiastic response from new invited authors.

The 25 chapters of this book examine many aspects of breast cancer, including: basic information on breast pathogenesis; prognostic factors; the mechanisms of estrogens formation and its control; breast cancer and pregnancy; the cellular origin of the disease; role of hormone receptors; action of anti-hormones and anti-growth factors; apoptosis; aromatase inhibitors; the role of androgens; chemoprevention (SERMs); action of LHRH analogs; the role of Vitamin D; insulin-like growth factor; the control of proliferation; importance of lignans and isoflavones; breast cancer and body size; anti-angiogenic therapy; cytotoxic therapy for the treatment of metastatic breast cancer and locally advanced breast cancer, BRCA1, BRCA2 and hereditary breast cancer.

Briefly, this book provides very recent updated information on a wide range of breast cancer aspects and should be useful for oncologists, endocrinologists, gynecologists, general clinicians, biologists, physiologists, and graduate students.

I would like to express my deep thanks to all the authors for their valuable contribution to their chapters as well as to Ms. Sandra Beberman and her colleagues of Informa Healthcare.