Cutaneous T-Cell Lymphoma: Mycosis Fungoides and Sezary Syndrome PDF

Preface

Although cutaneous T-cell lymphoma (CTCL) is relatively rare, it is of considerable interest to dermatologists as well as oncologists. One of the prime reasons for this is that CTCL is one of a relatively small number of dermatoses that has the potential for a fatal outcome. Particularly in its early stage, CTCL is often difficult to diagnose, both clinically and histologically. Further, CTCL has many forms of clinical presentations that may mimic other dermatoses.

The present volume presents an overview of the epidemiology and salient clinical and histologic features of mycosis fungoides, the most common form of CTCL. Related forms of CTCL, including Sezary syndrome, lymphomatoid papulosis, cutaneous CD30+ anaplastic large cell lymphoma, and follicular mucinosis, are reviewed. Immunochemistry and molecular techniques for diagnosis, as well as molecular abnormalities, are discussed. The volume concludes with a survey of the state-of-the-art treatment of CTCL and a section on staging and prognosis.