Genetic Predisposition to Cancer PDF

Preface

We are entering an era of genomic medicine in which conditions are starting to be defined by their underlying genomic changes. It is becoming increasingly clear that many diseases arise as a result of a genetic predisposition, either alone, or in conjunction with environmental changes which may exert greater effects on certain genetic backgrounds. Genetic predisposition to disease is also starting to have an effect on the type and efficacy of the treatment delivered. The practice of oncology is one of the mainstream areas of medicine where genomics will impact upon the care of a common condition. This book aims to inform health care practitioners in the field of oncology in the following areas: the basis of genetic predisposition, the cancer syndromes, the genetic basis of predisposition to the common cancers, early detection and management, and the ethicolegal and psychosocial issues surrounding the subject of genetic predisposition to cancer. We hope that this second edition of Genetic Predisposition to Cancer will be of interest to all those within the multidisciplinary team who work with cancer patients and their relatives.