Kidney: Toxicological Assessment PDF

Preface

Advances in genetics, toxicology, chemistry, and molecular biology have altered the way we perform toxicity assessment, and will profoundly infl uence our ability to diagnose, treat, and prevent organ injury induced by toxicants. In the near future, additional developments resulting from sequencing of the human genome, proteomics, small RNAs, and advances in combinatorial chemistry, micro-imaging, stem cell biology, and other areas of research are expected. This book strives to bridge the ever-increasing gap between the rapid advances in molecular biology and their applications to toxicity assessment. In collaboration with our publisher, Science Publishers, we provide 8 chapters in which we highlight areas of major progress in laboratory and clinical settings related to toxicity assessment. We as authors and editors will have achieved our goals if the reader fi nds within this volume glimpses into the current state and future directions of our discipline and perspectives that lead to better understanding of kidney toxicity assessment.