RNA-Seq in Drug Discovery and Development PDF

The research and development process in modern drug discovery and development

is a complex and challenging task. Using traditional biological test methods

such as PCR to measure the expression levels or function of these genes is costly

and time-consuming. RNA-seq can measure the expression patterns of thousands

of genes simultaneously and provide insights into functional pathways or regulations

in biological processes, which has revolutionized the way biological scientists

examine gene functions. This book addresses the various aspects of the

RNA-seq technique, especially its application in drug discovery and development.

Features

• One of the few books that focuses on the applications of the RNA-seq

technique in drug discovery and development

• Comprehensive and timely publication which relates RNA sequencing to

drug targets, mechanisms of action, and resistance

• The editor has extensive experience in the field of computational medicinal

chemistry, computational biophysics, and bioinformatics

• Chapter authors are at the frontline of the academic and industrial science

in this particular area of RNA sequencing

Authors: Feng Cheng, Robert Morris