Role of Oxidative Stress in Chronic Diseases PDF

Preface

The imbalance between pro-oxidants and antioxidants mechanisms is considered one of the most important pathophysiological mechanisms of chronic diseases. This lack of equilibrium may be responsible for both cause and/or consequences of chronic diseases. The incidence of chronic diseases is growing rapidly concomitant with aging of the population; cancer, metabolic, and neurodegenerative diseases are examples of these age-related chronic diseases. On the other hand, many transmissible chronic diseases have re-emerged or continue to affect the poorer regions of the world. This book intends to report the recent fi ndings of the role of oxidative stress in the aforementioned chronic diseases; understanding the mechanisms by which oxidative stress act on chronic diseases will enable us to comprehend the rationale which underlies intervention in such conditions. Clinical studies on humans can validate theoretical postulates concerning the benefi cial effects of different treatments.