ISPE Good Practice Guide: Heating, Ventilation, and Air Conditioning (HVAC) Second Edition PDF

Heating, Ventilation, and Air Conditioning (HVAC) design and operation play a crucial role in ensuring pharmaceutical facilities’ ability to safeguard product quality, operator and facility safety, occupant comfort, and environmental integrity.

Designing HVAC systems for the pharmaceutical industry involves unique considerations. These environments demand exceptionally clean and safe environments to protect both personnel and products. As a result, HVAC systems in pharmaceutical settings require higher levels of reliability, robustness, design scrutiny, and operational assurance compared to less stringent applications. Given that HVAC systems can consume a significant portion of the energy used by a facility, their design necessitates a blend of Good Engineering Practice (GEP) and Good Manufacturing Practice (GMP).