MWH Laboratories has developed a cost-effective, selective, and sensitive quantitative
method which can measure down to low ppt levels using a fully automated on-line
enrichment preparation technique followed by an LC-MS-MS analysis for water matrices
using novel techniques and tools such as scheduled Multiple Reaction Monitoring
(sMRM). Using a sensitive API 5000 LC-MS-MS, the method achieves reporting limits
in the ppt range for many of the analytes. This method eliminates the laborious off-line
enrichment which is usually needed to achieve the needed sensitivity for these pollutants
in water systems. In addition, the required small volume of less than 5 mls and the short
runs of 30 minutes injection to injection make this an ideal and fast method for water
screening and bench pilot studies.
This paper discusses the achievable Minimum Reporting Limit (MRL) using the
on-line enrichment technique, and further evaluates the precision and accuracy of
analyzing various types of water samples. The target list comprises over 80 compounds
of various classes, including EDCs, PPCPs, flame retardant, stimulants,
pesticides/herbicides, and their degradates. The method is currently part of a round-robin
study of analytical methods for emerging contaminants. Includes 13 references.
| Edition : | Vol. - No. |
| File Size : | 1
file
, 1.1 MB |
| Note : | This product is unavailable in Ukraine, Russia, Belarus |
| Number of Pages : | 9 |
| Published : | 11/01/2009 |
